Summary
XOFLX™ Packaging and Producer Cell Lines reduce/ eliminate plasmid transfection dependency, reducing manufacturing cost and process variability.
Upstream and downstream process developments for LVV production from Packaging cells improved process yield and recovery, and reduced required plasmid amount in transfection, enhancing the cost-saving benefit of the platform.
The Producer cell line allowed the development of an intensified LVV production process with multiple harvests, with the potential for the development of a perfusion process, which would significantly increase LVV batch yield and cost effectiveness of LVV manufacturing process.
Packaging and Producer Cell Lines are available for evaluation. Custom cell line development service is also available. Please contact business@oxgene.com for more information.