Resources

Poster: Accelerating Development and Manufacturing Platform for Viral Vector

Developing innovative advanced therapies is one of our greatest opportunities to dramatically improve patients’ lives. In this poster, we will discuss our recent technical advancement on efficient viral vector manufacturing process development. From cell line development, suspension culture of HEK293 cells, media optimization and purification process, a series of progress were implemented to advance our …Read More >

Resource Type: Poster
Resource Topic: Analytical Development Clinical & Commercial Manufacturing Process Development

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Virus clearance validation across continuous capture chromatography

Abstract Multicolumn capture chromatography is gaining increased attention lately due to the significant economic and process advantages it offers compared with traditional batch mode chromatography. However, for wide adoption of this technology in clinical and commercial space, it requires scalable models for executing viral validation studies. In this study, viral validation studies were conducted under …Read More >

Resource Type: Article
Resource Topic: Analytical Development

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Cell Line Authentication: Species Identity and Purity Analysis Using Next Generation Sequencing

December 2017 Cell Line Authentication: Species Identity and Purity Analysis Using Next Generation Sequencing Christine Mitchell, Scientific Fellow, Technical Development Group Cell Line Authentication assays using Targeted Next Generation Sequencing methods Cell Line Identity – Method overview Qualification of the Cell Line Identity Method Cell Line Purity – analyze for presence of 19 potentially contaminating …Read More >

Resource Type: Presentation
Resource Topic: Analytical Development Laboratory Testing

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