Resources

Accelerating Development and Manufacturing Platform for Viral Vector

Accelerating Development and Manufacturing Platform for Viral Vector Developing innovative advanced therapies is one of our greatest opportunities to dramatically improve patients’ lives. In this poster, we will discuss our recent technical advancement on efficient viral vector manufacturing process development. From cell line development, suspension culture of HEK293 cells, media optimization and purification process, a …Read More >

Resource Type: Poster
Resource Topic: Analytical Development Clinical & Commercial Manufacturing Process Development

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Virus clearance validation across continuous capture chromatography

Abstract Multicolumn capture chromatography is gaining increased attention lately due to the significant economic and process advantages it offers compared with traditional batch mode chromatography. However, for wide adoption of this technology in clinical and commercial space, it requires scalable models for executing viral validation studies. In this study, viral validation studies were conducted under …Read More >

Resource Type: Article
Resource Topic: Analytical Development

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Roundtable Discussion: Cell and Gene Therapies — Keep the Work In-House, or Use a Third Party?

During BIO 2019, BioProcess International hosted a roundtable discussion on “Cell and Gene Therapies – Keep the work in-house or use a third party” at BPI Theater. It was moderated by BioProcess Insider editor Dan Stanton with industry leaders that included Felix Hsu, Senior Vice President and Global Head of WuXi Advanced Therapies, Celonic Group, …Read More >

Resource Type: Video
Resource Topic: Clinical & Commercial Manufacturing

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Updates to Characterization Methods for Single Use Plastic Components Used In Pharmaceutical and Biopharmaceutical Manufacturing

This webcast features: Sandi Schaible, Senior Director, Analytical Chemistry and Regulatory Toxicology, WuXi AppTec Leachables from single use systems have the potential to impact the quality and safety of your drug product. This presentation will help you understand those risks and how to evaluate them, the current options for test methods and what the future holds …Read More >

Resource Type: Video
Resource Topic: Process Development

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Multibillion-Dollar Race for Gene Therapy Manufacturing

“Gene therapy, a promising therapeutic approach that corrects disease-causing genetic errors, has spurred an arms race among the world’s largest pharmaceutical companies. Novartis (NYSE: NVS) announced the acquisition of AxeVis for a whopping $8.7 billion in 2018. Roche (NASDAQOTH: RHHBY) agreed to acquire gene therapy developer Spark Therapeutics for $4.8 billion in early 2019. One week …Read More >

Resource Type: Article
Resource Topic: Clinical & Commercial Manufacturing

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